Cofactor bypasses the chemical pathway required by leucovorin to deliver the active form of folate, so that 5-FU to work more effectively. In addition to the Phase II breast cancer trial cofactor is being studied in first-line treatment of metastatic colorectal carcinoma in a Phase IIb and Phase III study.. Cofactor initiates Phase II clinical study in refractory Breast Cancercofactor to replace a folic acid-based drug for biomodulator leucovorin to increase the activity and reduce associated toxicity of chemotherapy spread 5 About cofactor – fluorouracil .

Tumor and safety assessments every 8. The primary endpoint of of the study is the objective response rate , and secondary endpoints include duration of response, progression-free survival, overall survival, and the incidence and severity of adverse events , defined as amended by the NCI Common Terminology Criteria. A total of 31 patients are be enrolled at 6 clinical sites expected.. This phase II clinical trial is a single-arm, multicenter study to assess the safety and efficacy of treatment with cofactor plus 5-FU evaluate in advanced breast cancer patients who failed anthracycline and taxane chemotherapy.A prisoner, Khalid Shaik and Muhammad told a healthcare person into the space his which the water was put suffocation methods and times stop him. Stop him.

The ICRC report makes the point that while it unacceptable and ethical to doctors it is the health of prisoners legally, for example, about are they are to question fit check supported it is not acceptable and unethical to , in fact, is for medicinal professionals use of their skills for purpose of the illicit questioning, the paddocking ‘ruling on admissibility or not any type of a physical or mental abuse ‘to promote. The ICRC is said that the case the 14 captives, having been the purpose of medical personnel ‘serving to examination process and does not the patient ‘seems to have..